Pharmaceutical Industry

Pharmaceutical IndustryFAI offers testing services for characterizing reactivity, flammability and combustible dust hazards as well as support services for preventing and mitigating consequences due to unwanted reactivity and fires and explosions due to combustible dust. 

Testing Services

  • Provide adiabatic calorimeters to companies who routinely perform testing
  • Perform contract testing on desired reactions using reaction calorimetry
  • Perform contract testing on undesired reactions due to upset scenarios using adiabatic calorimetry
  • Perform flammability hazards for liquid/gas mixtures at a variety of conditions
  • Perform dust explosion testing to determine moisture content, particle size, explosion severity and sensitivity to ignition

Hazard Assessment

  • Apply calorimetry information to satisfy PSM requirements for Process Safety Information (PSI)
  • Identify reactive chemical hazards and thermal instability for storage or transportation
  • Conduct an on-site combustible dust hazard assessment based on applicable National Fire Protection Association (NFPA) standards

Consequence Analysis

  • Ensure design basis of emergency relief system design including effluent handling considerations are appropriate and adequate
  • Ensure compliance with API 520/521 and API 2000 standards

Safety Program Support

  • Ensure combustible dust hazard identification, prevention and mitigation strategies are incorporated into existing programs
  • Provide process development support to ensure safe scale-up throughout the development cycle
  • Determine critical process parameters to avoid or mitigate unwanted reactivity
  • Develop of customized scale-up program designed for safer operation at various stages
  • Audit of existing safety program with gap analysis
  • Independent safety assessment

Related Articles:

In Final Report on West Pharmaceutical Explosion, CSB Finds Inadequate Controls for Dust Hazards, Calls on North Carolina to Strengthen Fire Code on Combustible Dust